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Old 06-04-2008, 09:59 PM   #1
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Default Receptor burnout??

A dude I know has been pinning Test-Cyp for about 3 weeks now. At first he had increased aggression (pretty bad), more oily skin, and looked full all day. Now these effects have gone away over the past few days.. and everything seems to be back to baseline (aggression, pumps, etc).

The only thing I can think of is that he only pins quads and maybe his receptors are gettin kinda burned out? Or am I just crazy?
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Old 06-04-2008, 10:30 PM   #2
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Quote:
Originally Posted by PUSHINW8 View Post
A dude I know has been pinning Test-Cyp for about 3 weeks now. At first he had increased aggression (pretty bad), more oily skin, and looked full all day. Now these effects have gone away over the past few days.. and everything seems to be back to baseline (aggression, pumps, etc).

The only thing I can think of is that he only pins quads and maybe his receptors are gettin kinda burned out? Or am I just crazy?
You won't down regulate in three weeks. It is not that.

I would also say that in the first 3 weeks, if he is running on cyp only, his increase in aggression et al. are a placebo effect b/c cyp takes a while to kick in fully. I would not expect to see someone run cyp as a stand alone cycle to see the effects until the 4th week at the earliest. Cyp is a very long ester and it will take some time to reach an effective level in the blood.

Regards,
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Old 06-04-2008, 10:34 PM   #3
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Thx C.. i was hoping you would pop in and respond to this.
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Old 06-04-2008, 10:57 PM   #4
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Quote:
Originally Posted by PUSHINW8 View Post
A dude I know has been pinning Test-Cyp for about 3 weeks now. At first he had increased aggression (pretty bad), more oily skin, and looked full all day. Now these effects have gone away over the past few days.. and everything seems to be back to baseline (aggression, pumps, etc).

The only thing I can think of is that he only pins quads and maybe his receptors are gettin kinda burned out? Or am I just crazy?
A.) Like DrC said, the test hasn't fully kicked in yet, levels HAVE increased, but i'm sure most of those sides are just all in his head. After it has kicked in he may start to notice those effects, but they will start to subside with time due to re-stabilization.

B.) In reference to your quad comment: AAS do not have site-specific growth.

C.) Receptors don't downregulate with AAS

Quote:
Originally Posted by DR_C View Post
You won't down regulate in three weeks. It is not that.

I would also say that in the first 3 weeks, if he is running on cyp only, his increase in aggression et al. are a placebo effect b/c cyp takes a while to kick in fully. I would not expect to see someone run cyp as a stand alone cycle to see the effects until the 4th week at the earliest. Cyp is a very long ester and it will take some time to reach an effective level in the blood.

Regards,
You won't downregulate at all.
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Old 06-04-2008, 11:07 PM   #5
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thx gix..
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Old 06-05-2008, 08:40 AM   #6
 
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what about the pumps then ? placebo as well ?
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Old 06-05-2008, 08:54 AM   #7
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Quote:
Originally Posted by LLLLern View Post
what about the pumps then ? placebo as well ?
In 3 weeks his test levels will have raised, but they arn't optimal yet...

could his pumps be placebo? of course they could. Could he just be making it up? Of course he could...
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Old 06-05-2008, 02:04 PM   #8
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C.) Receptors don't downregulate with AAS



You won't downregulate at all.
You are right Gixxer. There is no actual "down regulation" in AAS receptors. At least none that hte litureature has demonstrated. That is a nasty word stuck in my vocabulary from the 80's. The word I should have used is "desensitized."

Regulation is a wholely different process.

Thanks for catching that.

Regards,
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Old 06-05-2008, 02:36 PM   #9
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Does this friend post on LB under the screen name PUSHINW8?
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Old 06-05-2008, 03:55 PM   #10
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Quote:
Originally Posted by DR_C View Post
You are right Gixxer. There is no actual "down regulation" in AAS receptors. At least none that hte litureature has demonstrated. That is a nasty word stuck in my vocabulary from the 80's. The word I should have used is "desensitized."

Regulation is a wholely different process.

Thanks for catching that.

Regards,
Exactly!
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