When you get to it, long-term proviron on prostate

[hullcrush]

I know your time is valuable, long preface though.

3 years ago (when I was 19) I got mononucleosis from a fellow wrestler. The sequelae from that has been enormous, I used to be able to run 10 miles per day plus practice after classes. Now, I can barely run a mile. The only relief I get it 40 mg prednisone / day. As you can see, this is contradictory towards my goals, so I do not use it. I'm too tired to workout, so I just stretch. It drives me insane.

I'm not fucking lazy either... taking chemistry/physics classes while wrestling varsity while having an illness made my life awesome. I never took AAS while in sports. Either pulling weight or mono effed me up pretty bad. (Blood work STILL comes back relatively unremarkable, RBC usually elevated a bit).

Due to the structural similarities of prednisone and AAS, I was hoping to get some relief from proviron. I've taken one 2-week cycle of Anavar with 50% improvement (works great for flu, too) but I get shutdown after two weeks, not to mention its methylation and lack of legality (ie for a 22 y/o w/o HIV). I'm worried about long term prostate problems with Proviron, though. I understand Proviron will not solve my problem, so would it be safe to take it until I... die?

I profusely apologize for the length. Not looking for empathy, (your an MD, that's not allowed) looking for tips and science to at least let me run 3 miles a day.

[dinoiii]

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I'm not certain I fully understand your case based on the information given alone. Has your doctor suggested that the mono is the result of this long-term "windedness" that you describe?

There are some other things that jump out at me that could also defined generalized fatigue and malaise outside of continued infection.

It is NOT unheard of, albeit very rare, for a case of mono to extend up to several years after the active bout usually defined by the prototype. Still, this is a viral (Epstein-Barr Virus or EBV) illness (meaning that it is most likely that it will be self-limited or go away on its own). In that scenario, your immune system responds for long periods of time to various pathogens and could often use some fostering.

One of the key nutrients may very well be Folate (also suggested as Vitamin B9 on rare occasions for the scientific community) that your immune system needs more of to make new cells and antibodies. Blood levels of folate were tested in 260 patients with a variety of viral and other infections, 15 of whom were infected with EBV. Nine of these 15 patients with mono had insufficient amounts of folate; patients with other infections had similar deficiencies. The authors of the study suggest that the folate shortage may relate to fatigue and a long recovery period following a viral infection, including EBV. It is not definitive without additional research, but taking folate supplements may improve recovery.

Because of the POTENTIAL extension of this illness - this may be a sound investment (although I remain unconvinced at present to settle on that being the sole answer for you at this time based on all information presented).

No scientific studies have reviewed the value of herbs in treating EBV specifically. However, herbalists may use herbs that boost the immune system to try to prevent or treat viral infections in general. Echinacea (Echinacea spp.), wild indigo (Baptisia tinctoria), and licorice (Glycyrrhiza glabra) are used in acute conditions to boost immunity and improve the flow of lymph. Retinoic acid and glycyrrhetinic acid are derivatives of licorice root (Glycyrrhiza glabra) and may be used for similar purposes. Astragalus (Astragalus membranaceus) and lomatium (Lomatium dissectum), which have deeper immune-enhancing properties, are used to treat established infections or chronic problems.

Proviron is a rather interesting choice. But to explicitly answer your question...I would NOT encourage lifetime use of this agent for pure endocrinologic rationale rather than prostate woes in exclusion and this is certainly not the best of ideas if you ever intend on having children.

So - lets break it down molecularly to see what the heck I am talking about. This agent is already 5-alpha-reduced so its potential to cause estrogenic activity isn't there and we know in 2008 that estrogen is certainly implicated much more than testosterone and/or derivatives, analogues in the pathophysiology of prostate growth. In fact, many label it an anti-estrogen or anti-aromatase which it may very well be There is still a pretty high androgenic level associated with 5-Alpha reduced agents and as a result will surely prove suppressive in the long-run affecting many various pathways not exclusive to the HPTA.

Have you had any blood work recently?



Those may be some starting points, but please get back to me on whether or not your doctor has suggested that you remain incapacitated due to the virus rather than some other potential cause.


D_