The doctor's take on Prime

[CincoUno]

I don't have an ingredient panel for it yet, but judging from the blog ad they have up it seems to include:
Terminelia Chebula and some special extract of Tribulus Aquaticus.

Also in your estimation will combining Powerful, Anabolic Pump and Prime offer a similar transformation for me in 90 days?

[Right Hook]

Lmfao, this should be good. Good post. Here is more info for D_:

It’s just another Tribulus product. It’s a rip off. What’s up with that?

Have you tried it? Remember, it IS a different species, with a completely different make-up…
It’s not our fault the compound happens to be in the same family as tribulus terrestris
…It’s like comparing a donkey to a horse (who wins in a race?), same family, different species.

We have worked VERY hard to bring you cutting-edge products and earn your trust. We wouldn’t throw it away with releasing “another tribulus product”.

If you are skeptical then don’t buy the product. It’s really as simple as that.

What is the exact Mechanism of Action?

We are proposing that it may work through an anti-glucocorticoid effect or perhaps by acting as a calpain inhibitor, but this is speculation based upon our pilot study, anecdotal notes & lab values. We're certain that it doesn't work through an androgenic mechanism.

Proposed mechanisms of action are great and are ideal if available, but more important factors are if the product is thought to be safe and effective.

Pointing back to drugs as an example, there are many on the market which have only proposed mechanisms or the mechanism of action is not understood very well and is mainly speculative or hypothetical.

For example, the drug modafinil, once popular with many athletes; the exact mechanism through which it promotes a state of wakefulness is unknown. This is noted by the manufacturer and can be found on the package insert.

For many drugs, it is the same case (e.g. pramipexole, the entire family of benzodiazepines, etc.). The exact mechanism through which something works is not treated as highly as knowing that it is A) safe (defined through clinical endpoints--hepatic, renal, cardiac, neurologic, hematologic evaluations in humans, etc.) and B) effective. All evidence that we have indicates the product is both. We have not noted or received any reports of adverse effects with our own testing and the plant itself has enjoyed a long history of safe consumption prior.

Naive people who have never worked in clinical research or with FDA, might believe that each and every drug or supplement they take has a clear and well established mechanism of action and they are completely wrong.

In most cases, there are nothing more than proposed mechanisms which seem to fit clinical data and as already noted previously, some are nothing more than a hypothesis with the actual mechanism of action remaining unknown. Why a supplement company would be held to higher standards than those FDA subjects drug companies is beyond comprehension.

A final note: One cannot help but be curious as to where such reservations were when it has come to the countless products currently on the market. Products from plants where the compound is sold in pure form have the compound only making up .000001% of the actual plant. Products which have never actually been consumed by humans in their normal diet in any part of the world, despite being naturally occurring, result in no history of use in humans. Or, worst of all, products which do not even fall under the DSHEA; products which have never been found in naturally occurring sources to begin with and could be looked at as unapproved drugs. These products have never been studied for mechanism of action, safety, or efficacy; have no past history of use to base recommendations on and yet it seems they are not questioned. This seems odd.

[CincoUno]

From the sounds of it they had to travel to the center of the earth to obtain this extract.

[Right Hook]

Originally Posted by CincoUno

From the sounds of it they had to travel to the center of the earth to obtain this extract.

This was a good thread involving PA an LB Mod and others that basically went no where fast...

USPLABS Prime - Mind and Muscle Forums

[CincoUno]

that thread was good for a laugh I've got to check that site out more often.

[dinoiii]

Do I really have to acknowledge this?

This is one of the companies that labels the sports supplement sector of the industry. There is an integrity involved to not getting sucked into this trap guys.

I do NOT eliminate the potential of many compounds and you are aware of that. The problem lies both with marketing and abuse of the science behind the design. In other words, there is none. The dosing is even bull in many scenarios which leaves many disillusioned.



D_

[CincoUno]

Have you seen any evidence of Terminelia Chebula having benefits in these areas:
* Also contains antioxidant components, which indicates it may increase the life of tissues.

* In Ayurveda, Terminalia Chebula is used for 'Srotoshodhana' or purifying the channels of body

* It's thought to stimulate & protect the liver.

* When taken with meals, it's believed to sharpen the intellect, increases strength, stimulates the senses, expel urine, stool and other waste materials from the body.

* It's used in nervous weakness & irritability. It promotes the receiving power of the five senses.

* Based on its comprehensive properties, it promotes appetite and helps indigestion.

*CNS and body adaptagenic

I've never heard of this compound?

[usf97j4x4]

We're about to release this new product, they are called carbolic smoke balls, you suck on them and they keep you from getting the flu, and make your muscles huge. Their mechanism of action has yet to be determined.

[Supa-T]

Originally Posted by usf97j4x4

We're about to release this new product, they are called carbolic smoke balls, you suck on them and they keep you from getting the flu, and make your muscles huge. Their mechanism of action has yet to be determined.

Dude, there is no way you're getting your balls near my mouth

[Supa-T]

Originally Posted by CincoUno

I don't have an ingredient panel for it yet, but judging from the blog ad they have up it seems to include:
Terminelia Chebula and some special extract of Tribulus Aquaticus.

Also in your estimation will combining Powerful, Anabolic Pump and Prime offer a similar transformation for me in 90 days?

This is a load of horse crap. The guy went and lifted and maybe took an NO product. then they changed the lighting, angle and applied some make-up and poof, 1.5 hrs later...

Edit: and he lost the stupid visor