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4 - pSARM - Next generation pSARM with androgen-like effects.
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a "SARM-like" with androgen properties (hairloss,...)??
I thought the good of the real SARMs is that it has good oral bioavailability and anabolic properties without androgenic sides:
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They try to find compounds with high selectivity for the androgen receptor, with good anabolic and no androgenic activity.
These compounds are called Selective Androgen Receptor Modulator or SARM's. They should improve muscle strength, give more energy, stimulate a better mood, libido and sexual performance, without detrimental effects on the prostate, liver, heart and blood vessels. In women they should deal with frailty and osteoperose without virilizing effects
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http://www.ergogenics.org/anabolenboek/index20en.html
BTW, it seems to be very difficult for a supplement company to make a
REAL S.A.R.M.s:
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The anabolic steroids have ended up ultimately in the grey and black zone of doping and designer supplements. Maybe that will happen also with SARM's in the future. There are however a few differences between SARM's and anabolic steroids.
A SARM with high anabolic activity that is attractive for sportsmen and bodybuilders, still has to be found. When this will happen, the makers of designer SARM's and illegal supplements have a problem. It is not that easy to change the structure of a SARM a bit, to enhance its anabolic activity or to circumvent patents. Any minor change in its chemical structure may change an agonist into an antagonist. This last remark should be a warning for chemical sportsmen that are offered designer SARM's. They just as well may have an opposite effect.
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