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Old 04-27-2008, 02:49 PM   #1
 
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Question clomid question...

since clomid has two different isomers in it(enclomiphene and zuclomiphene)and the former acts as an E antagonist while the latter as an E agonist with a longer halflife...could this difference in their time activity cause futher HPTA suppression several days after the drug's discontinuation?could be useful add a pure E antagonist immediately after the clomid for a few days?any update about ANDROXAL's commercial availability? thank you D
Old 05-02-2008, 12:53 PM   #2
 
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Quote:
Originally Posted by xtyler View Post
since clomid has two different isomers in it(enclomiphene and zuclomiphene)and the former acts as an E antagonist while the latter as an E agonist with a longer halflife...could this difference in their time activity cause futher HPTA suppression several days after the drug's discontinuation?could be useful add a pure E antagonist immediately after the clomid for a few days?any update about ANDROXAL's commercial availability? thank you D
Theoretically perhaps, but this doesn't seem to translate into lab data we have.

That said, we also usually employ a relative "ramp down" with Clomid as well so this is very controlled settings used by us.

Meanwhile aromatase has the potential to increase as HPTA function comes back in line (especially with concurrent hCG therapy), which is why a concurrent AI would be ideally "ramped up" in dosing at this time.

As for ANDROXAL - are you referencing availability through your doctor?



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Old 05-02-2008, 03:09 PM   #3
 
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As for ANDROXAL - are you referencing availability through your doctor?



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