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**Sampson** · 06-13-2007, 03:41 PM

What exactly is going on in your body when you take prohormones that allows you to gain 10 lbs+ in a matter of four weeks? I understand that it increases protein synthesis, how does it do this? What else do they do other than increase protein synthesis? Why is it hard on your liver, blood pressure, hair line, ect. There are a lot of questions that I have about prohormones, as I don't completely understand how they work. Hopefully someone here can fill me in!

**RisingAgainst** · 06-13-2007, 03:44 PM

Quote:

Originally Posted by LeanBulk

What exactly is going on in your body when you take prohormones that allows you to gain 10 lbs+ in a matter of four weeks? I understand that it increases protein synthesis, how does it do this? What else do they do other than increase protein synthesis? Why is it hard on your liver, blood pressure, hair line, ect. There are a lot of questions that I have about prohormones, as I don't completely understand how they work. Hopefully someone here can fill me in!

1) Increased amount of protein in your muscles themselves.
2) Increased amounts of 'building material' AND increased call for building (test)
3) It increases your free test with synthetic free test, which still uses the same receptors, just different actions/pathways
4) Not all are 'hard on the liver', methylated ones are.
5) Blood pressure elevations is due to more blood in your system.
6) Hair line issues are from ph's that convert to DHT, which in turn is hard on the hair line, more so if you're already a MPB case.
7) Summary: don't do drugs, they fuck with your dick!

**Sampson** · 06-13-2007, 03:48 PM

Okay, I somewhat understand what the prohormones do, but how exactly do they do it? What is going on inside my body when I take prohormones?

**RisingAgainst** · 06-13-2007, 04:09 PM

Quote:

Originally Posted by LeanBulk

Okay, I somewhat understand what the prohormones do, but how exactly do they do it? What is going on inside my body when I take prohormones?

Well, depending on the particular ph ingested, it goes into your blood stream where it's broken down via enzymes and in some cases converted, in some cases not into actives and those 'actives' bind to receptors and the receptors send a signal to the brain to produce more X and Y.

thesinner · 06-13-2007, 04:21 PM

Quote:

Originally Posted by LeanBulk

Okay, I somewhat understand what the prohormones do, but how exactly do they do it? What is going on inside my body when I take prohormones?

This is actually too vague of a question to answer. The slightest change in structure can drastically change the pharmakinetics of the compound.

**Sampson** · 06-13-2007, 04:34 PM

yes it is a very broad question, and probably not one that can be completely answered. RA did a nice job though, thats about what I was looking for. I am sure it is much more complicated than this though

thesinner · 06-13-2007, 08:02 PM

Quote:

Originally Posted by RisingAgainst

Summary: don't do drugs, they fuck with your dick!

Girls tend to do the same thing. Should I not do them either?

Quote:

Originally Posted by LeanBulk

yes it is a very broad question, and probably not one that can be completely answered. RA did a nice job though, thats about what I was looking for. I am sure it is much more complicated than this though

Probably your best bet is to do the following:
1) Find out what the target active hormone is.
2) Google search "Steroid Profiles ________" (where the blank is where you put the target hormone). I really like the profiles on steroid.com they go pretty in-depth and contain plenty of citations. Only issue is that they don't always have the one's I'm looking for, and they have a lot of obscure ones that no one uses.