Albuterol Study

**Travis** · 05-13-2008, 08:16 PM

Study used an extended release form of albuterol at 12mg/day. Also it was completed on boys between the ages of 6 to 11. So one can assume these individuals were very light weight. This makes me think a male around 200lbs would need at least 24mg's or more...

Other thoughts?

Quote:

Neurology. 2008 Jan 8;70(2):137-43. Epub 2007 Oct 17.
Albuterol increases lean body mass in ambulatory boys with Duchenne or Becker muscular dystrophy.
Skura CL, Fowler EG, Wetzel GT, Graves M, Spencer MJ.

David Geffen School of Medicine at UCLA, 635 Charles Young Drive South, NRB1 Room 401, Los Angeles, CA 90095-7334, USA.

BACKGROUND: Albuterol is a beta-2 agonist that has been demonstrated to increase muscle strength in studies in animals and humans. Based on a pilot study of extended-release albuterol Repetabs in children with dystrophinopathies, the authors conducted a randomized, double-blind, placebo-controlled study with a crossover design. METHODS: Fourteen boys with Duchenne or Becker muscular dystrophy, 6 to 11 years old, completed two treatment periods (albuterol and placebo), 12 weeks each, separated by a 12-week washout period. As the albuterol Repetab formulation was no longer available, an alternate extended release albuterol was used (Volmax, 12 mg per day). Outcome measurements included 1) lean body mass, 2) fat mass, 3) isometric knee extensor and flexor moments, 4) manual muscle testing, and 5) timed functional tests. RESULTS: Lean body mass was significantly higher for subjects following albuterol treatment compared to placebo treatment, while fat mass was significantly lower. No differences were found in isometric knee moments or manual muscle tests. Time to run/walk 30 feet was improved following albuterol. CONCLUSIONS: Short-term treatment with extended release albuterol may increase lean body mass, decrease fat mass, and improve functional measures in patients with dystrophinopathies. However, the significant change in strength of specific muscle groups found in the pilot study was not observed in the present study. These findings may be attributed to differences in the drug release and kinetics between Repetab and Volmax formulations as they affect the concentration of available beta-2 receptors on the muscle cell surface differently.

TerribleTowel · 05-14-2008, 10:20 AM

Good find travis. Further confirmation that albuterol exhibits anabolic effects within humans. Interesting conclusion you made about the doses and it seems to likely that a higher dose, around 24 mg or so per day, would be needed to show affects in individuals of 200 pounds or more. This is definitely higher than what I normally see recommended. I have a couple bottles sitting here, but I have yet to try them.

Travis, have you ever ran albuterol?

jomi822 · 05-14-2008, 02:17 PM

i effin told you guys this stuff was anabolic! ugh!

**mad dog** · 05-14-2008, 02:51 PM

Quote:

Originally Posted by Travis

Study used an extended release form of albuterol at 12mg/day. Also it was completed on boys between the ages of 6 to 11. So one can assume these individuals were very light weight. This makes me think a male around 200lbs would need at least 24mg's or more...

Other thoughts?

As usual excellent post Travis i have about 4 bottles and will start using them before summer for a couple weeks.

EasyEJL · 05-14-2008, 03:04 PM

damn, now I want to run off and order some

**mad dog** · 05-14-2008, 04:54 PM

Quote:

Originally Posted by EasyEJL

damn, now I want to run off and order some

Yeah study looks solid and i know albuterol is excellent for fat loss.

**Travis** · 05-14-2008, 05:01 PM

Quote:

Originally Posted by TerribleTowel

Good find travis. Further confirmation that albuterol exhibits anabolic effects within humans. Interesting conclusion you made about the doses and it seems to likely that a higher dose, around 24 mg or so per day, would be needed to show affects in individuals of 200 pounds or more. This is definitely higher than what I normally see recommended. I have a couple bottles sitting here, but I have yet to try them.

Travis, have you ever ran albuterol?

Yes I did last summer. I think on average I was only taking 8-12mg/day. Didnt notice much but it did improve cardio to some degree. I'm using it again (began today) at 20mg's/day for 22 days (its left over so I figured I'd use it).

It does tend to mess with my BP a bit but hawthorne seems to really help out.

Quote:

Originally Posted by jomi822

i effin told you guys this stuff was anabolic! ugh!

Why are you using clen then?

Also, the study used a longer acting form of albuterol, which seems quite interesting to me. The half life is said to be 4 hours. For me it seems a bit shorter but who knows.

**mad dog** · 05-14-2008, 05:05 PM

I am going to start using mine prob for 14-21 days at the study dose.

**Travis** · 05-14-2008, 05:12 PM

Quote:

Originally Posted by mad dog

I am going to start using mine prob for 14-21 days at the study dose.

The study was extremely long too (12 weeks), which surprised me. I wonder when the bulk of the fat loss and muscle gain occurred. I am using benadryl at night just to make sure receptors are aiight.

TerribleTowel · 05-14-2008, 05:41 PM

Quote:

Originally Posted by jomi822

i effin told you guys this stuff was anabolic! ugh!

There's a lot of studies out there that say that albuterol exhibits anabolism in humans, but most user feedback I have seen has been marginal. Most people report it as being effective for fat loss, but not near as effective as clen, and most users haven't reported being able to notice any anabolic effect. However, most users have used lower doses than what would be needed according to this study, 24 mg or so for a 200+ pound individual. Maybe that's the problem, users simply haven't been dosing it high enough.

I'm assuming you've ran albuterol jomi. How did you dose it and how long did you run it? Were you able to notice it's anabolic effects?