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Old 04-08-2008, 06:31 PM   #1
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LB members,

Cortisol can catabolize muscle and testicular tissue leading to smaller muscles and lower testosterone levels. That’s why it’s desirable to suppress, or at least control cortisol levels. The most important time to guard you body against the effects of cortisol is during PCT when Testosterone levels are low, and cortisol can easily dominate and wreck havoc on the body. (Testosterone is a primary antagonist of cortisol)

Many cortisol blocking supplements on the market include one of the many DHEA metabolites such as 7-keto DHEA (7-oxo DHEA), 7-beta DHEA or androstenetriol. Short term studies have shown that these pro-hormone based cortisol blockers can lower LH & FSH thus inhibiting natural testosterone production. (1,2) While these may be useful supplements during a cycle, they should be avoided for PCT.

Phosphatidylserine (PS) is a ‘non-hormonal’ cortisol blocker that can effectively lower cortisol levels. Rather than lowering testosterone production, PS can actually increase testosterone production. (3,4) PS works by reducing CRH and ACTH release from the pituitary, thus reducing cortisol release from the adrenal glands.

Unfortunately PS has been prohibitively expensive, until now. In order to bring you the most affordable PS on the net, we are offering a month’s supply of PS (800mg/day) for only 47.99 – AKA EndoAmp.

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Thank you loyal Primordial fans!

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1. Effects of Transdermal Application of 7-oxo-DHEA on the Levels of Steroid Hormones, Gonadotropins and Lipids in Healthy Men.
J Sulcova, et al.
Institute of Endocrinology 50: 9-18, 2001

2. Delayed effects of short-term transdermal application of 7-oxo-dehydroepiandrosterone on its metabolites, some hormonal steroids and relevant proteohormones in healthy male volunteers
Jarmila Sulcova, et al.
Institute of Endoacrinology 43 (2):221-227 2005

3. HORMONAL EFFECTS OF PHOSPHATIDYLSERINE DURING 2-WKS OF INTENSE WEIGHT TRAINING [Annual Meeting Abstracts]
Fahey, T. D.; Pearl, M.
California State University, Chico


4. Blunting by chronic phosphatidylserine administration of the stress-induced activation of the hypothalamo-pituitary-adrenal axis in healthy men.
Monteleone et al.
Eur J Clin Pharmacol 1992, 42(4):385-388
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Last edited by Primordial Performance; 04-09-2008 at 01:54 PM.
Old 04-08-2008, 06:49 PM   #2
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And you left off the other PS benefits! Lol, good stuff though man.
Old 04-08-2008, 07:08 PM   #3
 
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nice to bad im a broke @#$%^&* lol
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Old 04-09-2008, 11:52 AM   #4
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i want your products. all of them. kthnx.
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Old 04-09-2008, 12:29 PM   #5
 
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has anyone heard any feed back on this product??
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Old 04-15-2008, 06:21 PM   #6
 
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bump
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Old 04-15-2008, 06:27 PM   #7
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Quote:
Originally Posted by LLLLern View Post
has anyone heard any feed back on this product??
Its pretty new, but I'm going to use it in my next PCT. But that is WEEKS away.

I'm following some feedback from another guy on another board who to date has stated fat loss seems a bit easier with it then without it. Also reported a slightly improved mood using it. Poster is Kimbo on M&M.
Old 04-15-2008, 07:02 PM   #8
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Yeah, this and the Tea-3 I am thinking of adding to my cut stack coming up...
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Old 04-15-2008, 07:12 PM   #9
 
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Quote:
Originally Posted by Travis View Post
Its pretty new, but I'm going to use it in my next PCT. But that is WEEKS away.

I'm following some feedback from another guy on another board who to date has stated fat loss seems a bit easier with it then without it. Also reported a slightly improved mood using it. Poster is Kimbo on M&M.
thanks
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Old 04-15-2008, 11:25 PM   #10
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Effects of transdermal application of 7-oxo-DHEA on the levels of steroid hormones, gonadotropins and lipids in healthy men.

Sulcová J, Hill M, Masek Z, Ceska R, Novácek A, Hampl R, Stárka L.
Institute of Endocrinology, Prague, Czech Republic. jsulcova@endo.cz
The aim of this study was to investigate the effect of 7-oxo-DHEA (dehydroepiandrosterone) on the serum levels of steroid sexual hormones, gonadotropins, lipids and lipoproteins in men. 7-oxo-DHEA was applied onto the skin as a gel to 10 volunteers aged 27 to 72 years for 5 consecutive days. The single dose contained 25 mg 7-oxo-DHEA. Serum concentrations of testosterone, estradiol, cortisol, androstenedione, luteinizing hormone (LH), follicle-stimulating hormone (FSH), sex hormone binding globulin (SHBG), total cholesterol, HDL- and LDL-cholesterol, triglycerides, apolipoprotein A-I and B and lipoprotein(a) were measured before the beginning and shortly after the end of the steroid application. After the treatment, we noted the following significant changes: a decline of testosterone and estradiol levels, increase of LH, HDL-cholesterol and apolipoprotein A-I levels. The decrease of total cholesterol levels was of the borderline significance. A slight but significant increase was found in apolipoprotein B and lipoprotein(a). The most expressive was the fall of the atherogenic index. We suggest that the gel containing 7-oxo-DHEA might be a suitable drug for improving the composition of the steroid and lipid parameters in elderly men.
PMID: 11300231 [PubMed - indexed for MEDLINE]

the recommended dose of dermabolics 7-cort is 100mg (4 times the dose studied), seems like it helps lipids so it could be a good combo pct with tamoxifen, the study shows it increasing LH (so does tamoxifen) but decreasing test (adrenal shutdown of dhea?).. i would love to try some of the pp products if they were in my price range :-/

Last edited by drksun; 04-15-2008 at 11:33 PM.

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